Impaired Endothelial Vasomotor Function After Sirolimus-Eluting Stent Implantation
نویسندگان
چکیده
منابع مشابه
Impaired endothelial vasomotor function after sirolimus-eluting stent implantation.
BACKGROUND Sirolimus inhibits endothelial cell proliferation in vitro, but although the sirolimus-eluting stent (SES) is widely used because of the very low rates of in-stent restenosis, the influence of SES on coronary endothelial vasomotor function in humans is not well known. METHODS AND RESULTS The present study included 21 patients treated with SES, and 12 patients treated with conventio...
متن کاملEndothelial dysfunction after sirolimus-eluting stent placement.
n this issue of the Journal, Togni et al. (1) report that xercise-induced coronary vasomotion is abnormal in segents proximal and distal to sirolimus-eluting stents (SES) hen evaluated six months after deployment. While subects who had received bare-metal stents demonstrated ormal exercise-induced vasodilation, subjects with SES learly demonstrated paradoxical vasoconstriction in peritent segme...
متن کاملAntiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantation.
BACKGROUND The influences of antiplatelet therapy discontinuation on the risk of stent thrombosis and long-term clinical outcomes after drug-eluting stent implantation have not yet been addressed adequately. METHODS AND RESULTS In an observational study in Japan, 2-year outcomes were assessed in 10 778 patients undergoing sirolimus-eluting stent implantation. Data on status of antiplatelet th...
متن کاملStent thrombosis after successful sirolimus-eluting stent implantation.
BACKGROUND Stent thrombosis (ST) is a rare but devastating complication of coronary stent implantation, occurring in 0.5% to 1.9% of patients with bare metal stents. The incidence of ST with drug-eluting stents is less well studied, particularly among patients outside of clinical trials. METHODS AND RESULTS The aim of this study was to evaluate the incidence and potential risk factors for ST ...
متن کاملEndothelial dysfunction after drug eluting stent implantation.
Endothelial dysfunction has been implicated in the pathological process of coronary artery disease as well as an adverse event after coronary drug eluting stent (DES) implantation. In this review, an overview will be given of the evidence to date regarding the effects of coronary DES on endothelial function obtained from both clinical and experimental studies. Stenting in general and DES seem t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Journal
سال: 2007
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.71.220